Hmdb loader

HMDBP01691 (Vitamin K-dependent gamma-carboxylase) Metabolite Associations

Displaying all 13 metabolite protein links
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0000148Glutamic acid56-86-0ThumbC5H9NO4147.1293
147.053157781
  1. Zhu A, Sun H, Raymond RM Jr, Furie BC, Furie B, Bronstein M, Kaufman RJ, Westrick R, Ginsburg D: Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase. Blood. 2007 Jun 15;109(12):5270-5. Epub 2007 Feb 27. [PubMed:17327402 ]
  2. Lal S, Jada SR, Xiang X, Lim WT, Lee EJ, Chowbay B: Pharmacogenetics of target genes across the warfarin pharmacological pathway. Clin Pharmacokinet. 2006;45(12):1189-200. [PubMed:17112295 ]
HMDB0000464Calcium7440-70-2ThumbCa40.078
39.962591155		Not Available
HMDB0001377Oxygen7782-44-7ThumbO231.9988
31.989829244		Not Available
HMDB0001892Menadione58-27-5ThumbC11H8O2172.18
172.0524295
  1. Wang Z, Wang M, Finn F, Carr BI: The growth inhibitory effects of vitamins K and their actions on gene expression. Hepatology. 1995 Sep;22(3):876-82. [PubMed:7657295 ]
  2. Stafford DW: The vitamin K cycle. J Thromb Haemost. 2005 Aug;3(8):1873-8. [PubMed:16102054 ]
  3. Presnell SR, Stafford DW: The vitamin K-dependent carboxylase. Thromb Haemost. 2002 Jun;87(6):937-46. [PubMed:12083499 ]
HMDB0001967Carbon dioxide124-38-9ThumbCO244.0095
43.989829244		Not Available
HMDB0002111Water7732-18-5ThumbH2O18.0153
18.010564686		Not Available
HMDB0002972Vitamin K1 2,3-epoxide85955-78-8ThumbC31H46O3466.706
466.344695341		Not Available
HMDB0003555Vitamin K184-80-0ThumbC31H46O2450.6957
450.349780716
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Morris DP, Soute BA, Vermeer C, Stafford DW: Characterization of the purified vitamin K-dependent gamma-glutamyl carboxylase. J Biol Chem. 1993 Apr 25;268(12):8735-42. [PubMed:8473318 ]
  3. Tuan RS: Vitamin K-dependent gamma-glutamyl carboxylase activity in the chick embryonic chorioallantoic membrane. J Biol Chem. 1979 Feb 25;254(4):1356-64. [PubMed:105006 ]
  4. Reedstrom CK, Suttie JW: Comparative distribution, metabolism, and utilization of phylloquinone and menaquinone-9 in rat liver. Proc Soc Exp Biol Med. 1995 Sep;209(4):403-9. [PubMed:7638250 ]
  5. Tasatargil A, Cadir B, Dalaklioglu S, Yurdakonar E, Caglar S, Turkay C: Effects of vitamin K1 supplementation on vascular responsiveness and oxidative stress in a rat femoral osteotomy model. Cell Biochem Funct. 2007 Sep-Oct;25(5):485-90. [PubMed:16929463 ]
  6. Olson RE: The function and metabolism of vitamin K. Annu Rev Nutr. 1984;4:281-337. [PubMed:6380538 ]
HMDB0004198Phylloquinol572-96-3ThumbC31H48O2452.7116
452.36543078		Not Available
HMDB0015257Anisindione117-37-3ThumbC16H12O3252.2647
252.07864425
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
HMDB00603592,3-EpoxymenaquinoneThumbC21H24O3324.4135
324.172544634		Not Available
HMDB0060487MenaquinolThumbC21H26O2310.4299
310.193280076		Not Available
HMDB02454162,3-EpoxyphylloquinoneThumbC31H46O3466.6951
466.344695338		Not Available
Displaying all 13 metabolite protein links