| Identification |
|---|
| HMDB Protein ID
| HMDBP14562 |
| Secondary Accession Numbers
| None |
| Name
| Transforming growth factor beta receptor type 3 |
| Synonyms
|
- TGF-beta receptor type 3
- TGFR-3
- Betaglycan
- Transforming growth factor beta receptor III
- TGF-beta receptor type III
|
| Gene Name
| TGFBR3 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| negative regulation of cellular component movement |
| regulation of transforming growth factor beta receptor signaling pathway |
| BMP signaling pathway |
| intracellular signal transduction |
| angiogenesis |
| signal transduction |
| response to follicle-stimulating hormone stimulus |
| immune response |
| transforming growth factor beta receptor signaling pathway |
| cell migration |
| vasculogenesis |
| epithelial to mesenchymal transition |
| Cellular Component |
| extracellular space |
| collagen-containing extracellular matrix |
| external side of plasma membrane |
| cell surface |
| integral to membrane |
| Molecular Function |
| transforming growth factor beta binding |
| glycosaminoglycan binding |
| coreceptor activity |
| heparin binding |
| type II transforming growth factor beta receptor binding |
| transforming growth factor beta receptor binding |
| transforming growth factor beta-activated receptor activity |
| transforming growth factor beta receptor activity, type III |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 848 |
| Molecular Weight
| 93004.025 |
| Theoretical pI
| 6.589 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P35054 |
| UniProtKB/Swiss-Prot Entry Name
| TGBR3_PIG |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Moren A, Ichijo H, Miyazono K: Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors. Biochem Biophys Res Commun. 1992 Nov 30;189(1):356-62. doi: 10.1016/0006-291x(92)91566-9. [PubMed:1333192 ]
|
