Hmdb loader
Identification
HMDB Protein ID HMDBP14548
Secondary Accession Numbers None
Name Ventricular zone-expressed PH domain-containing protein homolog 1
Synonyms
  1. Protein melted
Gene Name VEPH1
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of signal transduction
negative regulation of SMAD protein signal transduction
Cellular Component
plasma membrane
Molecular Function
phosphatidylinositol-5-phosphate binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 833
Molecular Weight 94744.51
Theoretical pI 6.71
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q14D04
UniProtKB/Swiss-Prot Entry Name MELT_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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