| Identification |
|---|
| HMDB Protein ID
| HMDBP14237 |
| Secondary Accession Numbers
| None |
| Name
| Sialic acid-binding Ig-like lectin 5 |
| Synonyms
|
- Siglec-5
- Sialic acid-binding Ig-like lectin F
- Siglec-F
- mSiglec-F
|
| Gene Name
| SIGLEC5 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cell adhesion |
| regulation of endocytosis |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| lysosome |
| Molecular Function |
| monosaccharide binding |
| sialic acid binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 569 |
| Molecular Weight
| 61475.49 |
| Theoretical pI
| 8.259 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q920G3 |
| UniProtKB/Swiss-Prot Entry Name
| SIGL5_MOUSE |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Angata T, Hingorani R, Varki NM, Varki A: Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters. J Biol Chem. 2001 Nov 30;276(48):45128-36. doi: 10.1074/jbc.M108573200. Epub 2001 Sep 28. [PubMed:11579105 ]
|
