| Identification |
|---|
| HMDB Protein ID
| HMDBP14221 |
| Secondary Accession Numbers
| None |
| Name
| Agglutinin receptor |
| Synonyms
|
- SSP-5
|
| Gene Name
| SSPB |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| May bind sialic acid residues of salivary agglutinin (SAG) in a calcium-dependent reaction. The interaction of SAG with its receptor in various oral streptococci modulate bacterial colonization of oral tissue and is associated with reduced levels of dental caries. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| cell wall |
| Molecular Function |
| metal ion binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 164551.525 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P16952 |
| UniProtKB/Swiss-Prot Entry Name
| SSPB_STRGN |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Demuth DR, Golub EE, Malamud D: Streptococcal-host interactions. Structural and functional analysis of a Streptococcus sanguis receptor for a human salivary glycoprotein. J Biol Chem. 1990 May 5;265(13):7120-6. [PubMed:2185241 ]
- Demuth DR, Duan Y, Brooks W, Holmes AR, McNab R, Jenkinson HF: Tandem genes encode cell-surface polypeptides SspA and SspB which mediate adhesion of the oral bacterium Streptococcus gordonii to human and bacterial receptors. Mol Microbiol. 1996 Apr;20(2):403-13. doi: 10.1111/j.1365-2958.1996.tb02627.x. [PubMed:8733238 ]
- Douglas CW, Heath J, Hampton KK, Preston FE: Identity of viridans streptococci isolated from cases of infective endocarditis. J Med Microbiol. 1993 Sep;39(3):179-82. doi: 10.1099/00222615-39-3-179. [PubMed:8366515 ]
- Chung WO, Demuth DR, Lamont RJ: Identification of a Porphyromonas gingivalis receptor for the Streptococcus gordonii SspB protein. Infect Immun. 2000 Dec;68(12):6758-62. doi: 10.1128/IAI.68.12.6758-6762.2000. [PubMed:11083792 ]
|
