| Identification |
|---|
| HMDB Protein ID
| HMDBP14172 |
| Secondary Accession Numbers
| None |
| Name
| Ribose-phosphate pyrophosphokinase 1 |
| Synonyms
|
- RPPK 1
- 5-phospho-D-ribosyl alpha-1-diphosphate 1
- Phosphoribosyl diphosphate synthase 1
- Phosphoribosyl pyrophosphate synthase 1
- P-Rib-PP synthase 1
- PRPP synthase 1
- PRPPase 1
|
| Gene Name
| PRS1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). |
| Pathways
|
- 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Carbon metabolism
- Microbial metabolism in diverse environments
- Pentose phosphate pathway
- Purine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| nucleotide biosynthetic process |
| nucleoside metabolic process |
| 5-phosphoribose 1-diphosphate biosynthetic process |
| ribonucleoside monophosphate biosynthetic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| magnesium ion binding |
| ATP binding |
| kinase activity |
| ribose phosphate diphosphokinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 322 |
| Molecular Weight
| 35283.515 |
| Theoretical pI
| 6.542 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q8E2H0 |
| UniProtKB/Swiss-Prot Entry Name
| KPRS1_STRA5 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Tettelin H, Masignani V, Cieslewicz MJ, Eisen JA, Peterson S, Wessels MR, Paulsen IT, Nelson KE, Margarit I, Read TD, Madoff LC, Wolf AM, Beanan MJ, Brinkac LM, Daugherty SC, DeBoy RT, Durkin AS, Kolonay JF, Madupu R, Lewis MR, Radune D, Fedorova NB, Scanlan D, Khouri H, Mulligan S, Carty HA, Cline RT, Van Aken SE, Gill J, Scarselli M, Mora M, Iacobini ET, Brettoni C, Galli G, Mariani M, Vegni F, Maione D, Rinaudo D, Rappuoli R, Telford JL, Kasper DL, Grandi G, Fraser CM: Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12391-6. doi: 10.1073/pnas.182380799. Epub 2002 Aug 28. [PubMed:12200547 ]
|
