| Identification |
|---|
| HMDB Protein ID
| HMDBP14023 |
| Secondary Accession Numbers
| None |
| Name
| Zinc finger protein 16 |
| Synonyms
|
Not Available
|
| Gene Name
| ZNF16 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Plays also a role as an inhibitor of cell apoptosis (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cell division |
| positive regulation of cell cycle phase transition |
| cellular response to sodium dodecyl sulfate |
| positive regulation of megakaryocyte differentiation |
| positive regulation of kinase activity |
| positive regulation of erythrocyte differentiation |
| regulation of transcription from RNA polymerase II promoter |
| cell cycle |
| positive regulation of cell division |
| negative regulation of apoptotic process |
| positive regulation of cell proliferation |
| Cellular Component |
| nucleoplasm |
| nucleolus |
| nucleus |
| Molecular Function |
| metal ion binding |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 682 |
| Molecular Weight
| 76322.935 |
| Theoretical pI
| 7.782 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A1YF12 |
| UniProtKB/Swiss-Prot Entry Name
| ZNF16_GORGO |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
