| Identification |
| HMDB Protein ID
| HMDBP14019 |
| Secondary Accession Numbers
| None |
| Name
| Carnosine N-methyltransferase 2 |
| Synonyms
|
- Histamine N-methyltransferase-like
- HNMT-like
|
| Gene Name
| (REFSEQ) CARNOSINE N-METHYLTRANSFERASE 2 |
| Protein Type
| Unknown |
| Biological Properties |
| General Function
| Not Available |
| Specific Function
| N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| methylation |
| carnosine metabolic process |
| Molecular Function |
| N-methyltransferase activity |
| carnosine N-methyltransferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
| Number of Residues
| 322 |
| Molecular Weight
| 36375.155 |
| Theoretical pI
| 6.04 |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| U3NEE3 |
| UniProtKB/Swiss-Prot Entry Name
| HNMTL_CHICK |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
| General References
| - Drozak J, Chrobok L, Poleszak O, Jagielski AK, Derlacz R: Molecular identification of carnosine N-methyltransferase as chicken histamine N-methyltransferase-like protein (hnmt-like). PLoS One. 2013 May 21;8(5):e64805. doi: 10.1371/journal.pone.0064805. Print 2013. [PubMed:23705015 ]
- Authors unspecified: Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 2004 Dec 9;432(7018):695-716. doi: 10.1038/nature03154. [PubMed:15592404 ]
|