| Identification |
|---|
| HMDB Protein ID
| HMDBP14006 |
| Secondary Accession Numbers
| None |
| Name
| Interferon alpha-1 |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| defense response to virus |
| B cell differentiation |
| humoral immune response |
| response to exogenous dsRNA |
| cytokine-mediated signaling pathway |
| B cell proliferation |
| adaptive immune response |
| natural killer cell activation involved in immune response |
| positive regulation of peptidyl-serine phosphorylation of STAT protein |
| T cell activation involved in immune response |
| Cellular Component |
| extracellular space |
| Molecular Function |
| cytokine activity |
| type I interferon receptor binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 21405.36 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P07348 |
| UniProtKB/Swiss-Prot Entry Name
| IFNA1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Capon DJ, Shepard HM, Goeddel DV: Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides. Mol Cell Biol. 1985 Apr;5(4):768-79. doi: 10.1128/mcb.5.4.768-779.1985. [PubMed:2985969 ]
|
