Hmdb loader
Identification
HMDB Protein ID HMDBP14004
Secondary Accession Numbers None
Name Homoserine O-succinyltransferase
Synonyms
  1. HST
  2. Homoserine transsuccinylase
  3. HTS
Gene Name METAS
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
Pathways
  • Biosynthesis of amino acids
  • Biosynthesis of secondary metabolites
  • Cysteine and methionine metabolism
  • L-methionine biosynthesis via de novo pathway
  • Sulfur metabolism
Reactions Not Available
GO Classification
Biological Process
L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Cellular Component
cytoplasm
Molecular Function
homoserine O-acetyltransferase activity
homoserine O-succinyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 309
Molecular Weight 35742.96
Theoretical pI 5.218
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID A1AII3
UniProtKB/Swiss-Prot Entry Name METAS_ECOK1
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Johnson TJ, Kariyawasam S, Wannemuehler Y, Mangiamele P, Johnson SJ, Doetkott C, Skyberg JA, Lynne AM, Johnson JR, Nolan LK: The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes. J Bacteriol. 2007 Apr;189(8):3228-36. doi: 10.1128/JB.01726-06. Epub 2007 Feb 9. [PubMed:17293413 ]