| Identification |
|---|
| HMDB Protein ID
| HMDBP14003 |
| Secondary Accession Numbers
| None |
| Name
| Homoserine O-succinyltransferase |
| Synonyms
|
- HST
- Homoserine transsuccinylase
- HTS
|
| Gene Name
| METAS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Cysteine and methionine metabolism
- L-methionine biosynthesis via de novo pathway
- Sulfur metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| homoserine O-acetyltransferase activity |
| homoserine O-succinyltransferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 309 |
| Molecular Weight
| 35670.04 |
| Theoretical pI
| 5.391 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5PKY6 |
| UniProtKB/Swiss-Prot Entry Name
| METAS_SALPA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]
|
