| Identification |
|---|
| HMDB Protein ID
| HMDBP13996 |
| Secondary Accession Numbers
| None |
| Name
| Homoserine O-acetyltransferase |
| Synonyms
|
- HAT
- Homoserine transacetylase
- HTA
|
| Gene Name
| METXA |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Cysteine and methionine metabolism
- L-methionine biosynthesis via de novo pathway
- Sulfur metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| methionine biosynthetic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| homoserine O-acetyltransferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 490 |
| Molecular Weight
| 55388.825 |
| Theoretical pI
| 6.802 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q2NGH9 |
| UniProtKB/Swiss-Prot Entry Name
| METXA_METST |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Fricke WF, Seedorf H, Henne A, Kruer M, Liesegang H, Hedderich R, Gottschalk G, Thauer RK: The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis. J Bacteriol. 2006 Jan;188(2):642-58. doi: 10.1128/JB.188.2.642-658.2006. [PubMed:16385054 ]
- Bastard K, Perret A, Mariage A, Bessonnet T, Pinet-Turpault A, Petit JL, Darii E, Bazire P, Vergne-Vaxelaire C, Brewee C, Debard A, Pellouin V, Besnard-Gonnet M, Artiguenave F, Medigue C, Vallenet D, Danchin A, Zaparucha A, Weissenbach J, Salanoubat M, de Berardinis V: Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis. Nat Chem Biol. 2017 Aug;13(8):858-866. doi: 10.1038/nchembio.2397. Epub 2017 Jun 5. [PubMed:28581482 ]
|
