| Identification |
|---|
| HMDB Protein ID
| HMDBP13906 |
| Secondary Accession Numbers
| None |
| Name
| Phospholipase A1 verutoxin-2a |
| Synonyms
|
- VT-2a
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the hydrolysis of emulsified phosphatidylcholine (2258 umol/min/mg) and has a moderate activity to hydrolyze lysophosphatidylcholine (1018 umol/min/mg), but is unable to hydrolyze sphingomyelin. Shows a potent direct hemolytic activity on red blood cells of mice (98.8% of hemolysis at 3.0 ug/ml). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| lipid catabolic process |
| hemolysis in other organism |
| Cellular Component |
| extracellular region |
| Molecular Function |
| 1-acyl-2-lysophosphatidylserine acylhydrolase activity |
| phosphatidylcholine 1-acylhydrolase activity |
| phosphatidylserine 1-acylhydrolase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 3012.42 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P0DMB7 |
| UniProtKB/Swiss-Prot Entry Name
| PA12A_VESVE |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Ho CL, Lin YL, Li SF: Three toxins with phospholipase activity isolated from the yellow-legged hornet (Vespa verutina) venom. Toxicon. 1999 Jul;37(7):1015-24. doi: 10.1016/s0041-0101(98)00229-3. [PubMed:10484737 ]
|
