| Identification |
|---|
| HMDB Protein ID
| HMDBP13886 |
| Secondary Accession Numbers
| None |
| Name
| 6,7-dimethyl-8-ribityllumazine synthase |
| Synonyms
|
- DMRL synthase
- LS
- Lumazine synthase
|
| Gene Name
| RIBH |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. |
| Pathways
|
- Biosynthesis of cofactors
- Biosynthesis of secondary metabolites
- riboflavin biosynthesis
- Riboflavin metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| riboflavin biosynthetic process |
| Cellular Component |
| riboflavin synthase complex |
| Molecular Function |
| 6,7-dimethyl-8-ribityllumazine synthase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 156 |
| Molecular Weight
| 16008.135 |
| Theoretical pI
| 5.234 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5PFS8 |
| UniProtKB/Swiss-Prot Entry Name
| RISB_SALPA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]
|
