| Identification |
|---|
| HMDB Protein ID
| HMDBP13885 |
| Secondary Accession Numbers
| None |
| Name
| 6,7-dimethyl-8-ribityllumazine synthase |
| Synonyms
|
- DMRL synthase
- LS
- Lumazine synthase
|
| Gene Name
| RIBH |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. |
| Pathways
|
- Biosynthesis of cofactors
- Biosynthesis of secondary metabolites
- riboflavin biosynthesis
- Riboflavin metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| riboflavin biosynthetic process |
| Cellular Component |
| riboflavin synthase complex |
| Molecular Function |
| 6,7-dimethyl-8-ribityllumazine synthase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 155 |
| Molecular Weight
| 16952.53 |
| Theoretical pI
| 7.361 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9REF4 |
| UniProtKB/Swiss-Prot Entry Name
| RISB_BARHE |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Alsmark CM, Frank AC, Karlberg EO, Legault BA, Ardell DH, Canback B, Eriksson AS, Naslund AK, Handley SA, Huvet M, La Scola B, Holmberg M, Andersson SG: The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9716-21. doi: 10.1073/pnas.0305659101. Epub 2004 Jun 21. [PubMed:15210978 ]
- Bereswill S, Hinkelmann S, Kist M, Sander A: Molecular analysis of riboflavin synthesis genes in Bartonella henselae and use of the ribC gene for differentiation of Bartonella species by PCR. J Clin Microbiol. 1999 Oct;37(10):3159-66. doi: 10.1128/JCM.37.10.3159-3166.1999. [PubMed:10488170 ]
|
