Hmdb loader
Identification
HMDB Protein ID HMDBP13854
Secondary Accession Numbers None
Name Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Synonyms
  1. UDP-N-acetylglucosamine acyltransferase
Gene Name LPXA
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Pathways
  • Cationic antimicrobial peptide (CAMP) resistance
  • lipid IV(A) biosynthesis
  • Lipopolysaccharide biosynthesis
Reactions Not Available
GO Classification
Biological Process
lipid A biosynthetic process
Cellular Component
cytoplasm
Molecular Function
acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 262
Molecular Weight 28088.885
Theoretical pI 7.088
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q5PD73
UniProtKB/Swiss-Prot Entry Name LPXA_SALPA
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]