| Identification |
|---|
| HMDB Protein ID
| HMDBP13779 |
| Secondary Accession Numbers
| None |
| Name
| Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase |
| Synonyms
|
- Undecaprenyl-phosphate Ara4FN transferase
- Ara4FN transferase
|
| Gene Name
| ARNC |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. |
| Pathways
|
- 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis
- Amino sugar and nucleotide sugar metabolism
- Cationic antimicrobial peptide (CAMP) resistance
- lipopolysaccharide biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| response to antibiotic |
| lipopolysaccharide biosynthetic process |
| lipid A biosynthetic process |
| 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| Molecular Function |
| phosphotransferase activity, for other substituted phosphate groups |
| undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 327 |
| Molecular Weight
| 36475.83 |
| Theoretical pI
| 6.648 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5PNA5 |
| UniProtKB/Swiss-Prot Entry Name
| ARNC_SALPA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]
|
