| Identification |
|---|
| HMDB Protein ID
| HMDBP13765 |
| Secondary Accession Numbers
| None |
| Name
| Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase |
| Synonyms
|
- 4-amino-4-deoxy-L-arabinose lipid A transferase
- Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase
- Undecaprenyl phosphate-alpha-L-Ara4N transferase
|
| Gene Name
| ARNT |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. |
| Pathways
|
- 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis
- Cationic antimicrobial peptide (CAMP) resistance
- Lipopolysaccharide biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| lipopolysaccharide biosynthetic process |
| protein O-linked glycosylation |
| lipid A biosynthetic process |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| Molecular Function |
| mannosyltransferase activity |
| 4-amino-4-deoxy-L-arabinose transferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 550 |
| Molecular Weight
| 62564.015 |
| Theoretical pI
| 8.988 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 7-27;81-101;111-133;137-154;165-185;204-224;263-283;288-308;315-335;346-366;382-402;406-426;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A1ADA9 |
| UniProtKB/Swiss-Prot Entry Name
| ARNT_ECOK1 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Johnson TJ, Kariyawasam S, Wannemuehler Y, Mangiamele P, Johnson SJ, Doetkott C, Skyberg JA, Lynne AM, Johnson JR, Nolan LK: The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes. J Bacteriol. 2007 Apr;189(8):3228-36. doi: 10.1128/JB.01726-06. Epub 2007 Feb 9. [PubMed:17293413 ]
|
