| Identification |
|---|
| HMDB Protein ID
| HMDBP13760 |
| Secondary Accession Numbers
| None |
| Name
| Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase |
| Synonyms
|
- 4-amino-4-deoxy-L-arabinose lipid A transferase
- Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase
- Undecaprenyl phosphate-alpha-L-Ara4N transferase
|
| Gene Name
| ARNT |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. |
| Pathways
|
- 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis
- Cationic antimicrobial peptide (CAMP) resistance
- Lipopolysaccharide biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| lipopolysaccharide biosynthetic process |
| protein O-linked glycosylation |
| lipid A biosynthetic process |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| Molecular Function |
| mannosyltransferase activity |
| 4-amino-4-deoxy-L-arabinose transferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 547 |
| Molecular Weight
| 61660.21 |
| Theoretical pI
| 9.146 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 8-28;81-101;113-133;136-156;162-184;204-224;255-275;288-308;310-330;344-364;380-400;404-424;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5PNA8 |
| UniProtKB/Swiss-Prot Entry Name
| ARNT_SALPA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]
|
