| Identification |
|---|
| HMDB Protein ID
| HMDBP13711 |
| Secondary Accession Numbers
| None |
| Name
| Tetraacyldisaccharide 4'-kinase |
| Synonyms
|
- Lipid A 4'-kinase
|
| Gene Name
| LPXK |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). |
| Pathways
|
- lipid IV(A) biosynthesis
- Lipopolysaccharide biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| lipid A biosynthetic process |
| Molecular Function |
| ATP binding |
| tetraacyldisaccharide 4'-kinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 322 |
| Molecular Weight
| 36144.885 |
| Theoretical pI
| 9.22 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A0Q8A0 |
| UniProtKB/Swiss-Prot Entry Name
| LPXK_FRATN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Rohmer L, Fong C, Abmayr S, Wasnick M, Larson Freeman TJ, Radey M, Guina T, Svensson K, Hayden HS, Jacobs M, Gallagher LA, Manoil C, Ernst RK, Drees B, Buckley D, Haugen E, Bovee D, Zhou Y, Chang J, Levy R, Lim R, Gillett W, Guenthener D, Kang A, Shaffer SA, Taylor G, Chen J, Gallis B, D'Argenio DA, Forsman M, Olson MV, Goodlett DR, Kaul R, Miller SI, Brittnacher MJ: Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biol. 2007;8(6):R102. doi: 10.1186/gb-2007-8-6-r102. [PubMed:17550600 ]
|
