| Identification |
|---|
| HMDB Protein ID
| HMDBP13700 |
| Secondary Accession Numbers
| None |
| Name
| Heat shock transcription factor |
| Synonyms
|
- HSTF
- Heat shock factor protein
- HSF
|
| Gene Name
| HSF1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription (PubMed:17040492). Together with its coregulator SSA1, activates expression of laccase LAC1 during glucose starvation (PubMed:17040492). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| regulation of transcription from RNA polymerase II promoter |
| Cellular Component |
| nucleus |
| Molecular Function |
| sequence-specific DNA binding |
| sequence-specific DNA binding transcription factor activity |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 783 |
| Molecular Weight
| 81500.3 |
| Theoretical pI
| 5.318 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q5KMX8 |
| UniProtKB/Swiss-Prot Entry Name
| HSF_CRYNJ |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu R, Doering TL, Donlin MJ, D'Souza CA, Fox DS, Grinberg V, Fu J, Fukushima M, Haas BJ, Huang JC, Janbon G, Jones SJ, Koo HL, Krzywinski MI, Kwon-Chung JK, Lengeler KB, Maiti R, Marra MA, Marra RE, Mathewson CA, Mitchell TG, Pertea M, Riggs FR, Salzberg SL, Schein JE, Shvartsbeyn A, Shin H, Shumway M, Specht CA, Suh BB, Tenney A, Utterback TR, Wickes BL, Wortman JR, Wye NH, Kronstad JW, Lodge JK, Heitman J, Davis RW, Fraser CM, Hyman RW: The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science. 2005 Feb 25;307(5713):1321-4. doi: 10.1126/science.1103773. Epub 2005 Jan 13. [PubMed:15653466 ]
- Zhang S, Hacham M, Panepinto J, Hu G, Shin S, Zhu X, Williamson PR: The Hsp70 member, Ssa1, acts as a DNA-binding transcriptional co-activator of laccase in Cryptococcus neoformans. Mol Microbiol. 2006 Nov;62(4):1090-101. doi: 10.1111/j.1365-2958.2006.05422.x. Epub 2006 Oct 16. [PubMed:17040492 ]
|
