Hmdb loader
Identification
HMDB Protein ID HMDBP13654
Secondary Accession Numbers None
Name Protoheme IX farnesyltransferase
Synonyms
  1. Heme B farnesyltransferase
  2. Heme O synthase
Gene Name CTAB
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
Pathways
  • Biosynthesis of cofactors
  • Biosynthesis of secondary metabolites
  • heme O biosynthesis
  • Oxidative phosphorylation
  • Porphyrin and chlorophyll metabolism
Reactions Not Available
GO Classification
Biological Process
heme O biosynthetic process
Cellular Component
integral to membrane
plasma membrane
Molecular Function
protoheme IX farnesyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 337
Molecular Weight 37486.04
Theoretical pI 9.778
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • 59-79;81-101;130-150;153-173;196-216;250-270;271-291;311-331;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q6A7G0
UniProtKB/Swiss-Prot Entry Name COXX_CUTAK
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Bruggemann H, Henne A, Hoster F, Liesegang H, Wiezer A, Strittmatter A, Hujer S, Durre P, Gottschalk G: The complete genome sequence of Propionibacterium acnes, a commensal of human skin. Science. 2004 Jul 30;305(5684):671-3. doi: 10.1126/science.1100330. [PubMed:15286373 ]