| Identification |
|---|
| HMDB Protein ID
| HMDBP13645 |
| Secondary Accession Numbers
| None |
| Name
| Protoheme IX farnesyltransferase |
| Synonyms
|
- Heme B farnesyltransferase
- Heme O synthase
|
| Gene Name
| CTAB |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. |
| Pathways
|
- Biosynthesis of cofactors
- Biosynthesis of secondary metabolites
- heme O biosynthesis
- Oxidative phosphorylation
- Porphyrin and chlorophyll metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| heme O biosynthetic process |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| Molecular Function |
| protoheme IX farnesyltransferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 306 |
| Molecular Weight
| 34033.595 |
| Theoretical pI
| 9.608 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 28-48;53-73;105-125;127-147;156-176;182-202;227-244;246-266;283-303;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| B9EB27 |
| UniProtKB/Swiss-Prot Entry Name
| COXX_MACCJ |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Baba T, Kuwahara-Arai K, Uchiyama I, Takeuchi F, Ito T, Hiramatsu K: Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402, [corrected] reflecting the ancestral genome of the human-pathogenic staphylococci. J Bacteriol. 2009 Feb;191(4):1180-90. doi: 10.1128/JB.01058-08. Epub 2008 Dec 12. [PubMed:19074389 ]
|
