| Identification |
|---|
| HMDB Protein ID
| HMDBP13643 |
| Secondary Accession Numbers
| None |
| Name
| Protoheme IX farnesyltransferase |
| Synonyms
|
- Heme B farnesyltransferase
- Heme O synthase
|
| Gene Name
| CTAB |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. |
| Pathways
|
- Biosynthesis of cofactors
- Biosynthesis of secondary metabolites
- heme O biosynthesis
- Oxidative phosphorylation
- Porphyrin and chlorophyll metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| heme O biosynthetic process |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| Molecular Function |
| protoheme IX farnesyltransferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 312 |
| Molecular Weight
| 34581.025 |
| Theoretical pI
| 9.454 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 33-53;54-74;105-125;126-146;154-174;181-201;243-263;291-311;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q6G4C6 |
| UniProtKB/Swiss-Prot Entry Name
| COXX_BARHE |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Alsmark CM, Frank AC, Karlberg EO, Legault BA, Ardell DH, Canback B, Eriksson AS, Naslund AK, Handley SA, Huvet M, La Scola B, Holmberg M, Andersson SG: The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9716-21. doi: 10.1073/pnas.0305659101. Epub 2004 Jun 21. [PubMed:15210978 ]
|
