| Identification |
|---|
| HMDB Protein ID
| HMDBP13595 |
| Secondary Accession Numbers
| None |
| Name
| Alpha-N-acetylgalactosaminidase |
| Synonyms
|
- Alpha-galactosidase B
|
| Gene Name
| NAGA |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| glycoside catabolic process |
| glycosylceramide catabolic process |
| oligosaccharide metabolic process |
| Cellular Component |
| cytoplasm |
| lysosome |
| Molecular Function |
| alpha-galactosidase activity |
| alpha-N-acetylgalactosaminidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 45614.87 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q90744 |
| UniProtKB/Swiss-Prot Entry Name
| NAGAB_CHICK |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Davis MO, Hata DJ, Smith D, Walker JC: Cloning and sequence of a chicken alpha-N-acetylgalactosaminidase gene. Biochim Biophys Acta. 1993 Nov 16;1216(2):296-8. doi: 10.1016/0167-4781(93)90158-a. [PubMed:8241271 ]
- Garman SC, Hannick L, Zhu A, Garboczi DN: The 1.9 A structure of alpha-N-acetylgalactosaminidase: molecular basis of glycosidase deficiency diseases. Structure. 2002 Mar;10(3):425-34. doi: 10.1016/s0969-2126(02)00726-8. [PubMed:12005440 ]
|
