| Identification |
|---|
| HMDB Protein ID
| HMDBP13525 |
| Secondary Accession Numbers
| None |
| Name
| Snake venom metalloproteinase BjussuMP-2 |
| Synonyms
|
- SVMP
- BOJUMET I
- BjussuMP-II
- Nonhemorrhagic metalloprotease MP-II
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| This metalloproteinase displays proteolytic activity on fibrin, fibrinogen, collagen, casein and gelatin. It inhibits ADP- and collagen-induced platelet aggregation and displays a very low edema inducing activity. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| metal ion binding |
| metalloendopeptidase activity |
| toxin activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 41956.76 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q7T1T4 |
| UniProtKB/Swiss-Prot Entry Name
| VM1B2_BOTJR |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Kashima S, Roberto PG, Soares AM, Astolfi-Filho S, Pereira JO, Giuliati S, Faria M Jr, Xavier MA, Fontes MR, Giglio JR, Franca SC: Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I--gene expression profile of highly expressed phospholipases A2. Biochimie. 2004 Mar;86(3):211-9. doi: 10.1016/j.biochi.2004.02.002. [PubMed:15134836 ]
- Marcussi S, Bernardes CP, Santos-Filho NA, Mazzi MV, Oliveira CZ, Izidoro LF, Fuly AL, Magro AJ, Braz AS, Fontes MR, Giglio JR, Soares AM: Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity. Peptides. 2007 Dec;28(12):2328-39. doi: 10.1016/j.peptides.2007.10.010. Epub 2007 Oct 22. [PubMed:18006118 ]
|
