| Identification |
|---|
| HMDB Protein ID
| HMDBP13497 |
| Secondary Accession Numbers
| None |
| Name
| Alpha-fibrinogenase shedaoenase |
| Synonyms
|
- Snake venom serine protease
- SVSP
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Snake venom protease that shows fibrinogenolytic activities. Preferentially degrades the alpha-chain of human fibrinogen (FGA) and slowly degrades the beta-chain (FGB). Has no effect on the gamma-chain. Can hydrolyze fibrinogen without forming fibrin clots and also can degrade fibrin. Hydrolyzes the substrate of plasmin more potently than the substrate of thrombin. Shows a preferential cleavage at Lys-|-Xaa instead of Arg-|-Xaa bonds. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| toxin activity |
| serine-type endopeptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 26415.925 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q6T5L0 |
| UniProtKB/Swiss-Prot Entry Name
| VSPSH_GLOSH |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Jiao HM, Yang LX, Lu B, Wu YQ, Zhou YC: Shedaoenase, a novel fibrinogenase from the venom of Agkistrodon shedaoenthesis Zhao. Acta Biochim Biophys Sin (Shanghai). 2005 Dec;37(12):835-42. doi: 10.1111/j.1745-7270.2005.00119.x. [PubMed:16331328 ]
|
