| Identification |
|---|
| HMDB Protein ID
| HMDBP13437 |
| Secondary Accession Numbers
| None |
| Name
| Snaclec lebecetin subunit alpha |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Binds to the platelet GPIb/IX/V receptor system and inhibits ristocetin-induced platelet aggregation in human platelet-rich plasma. Strongly inhibits platelet aggregation induced by ADP, calcium ionophore, thrombin and collagen. Does not inhibit U46619-induced platelet aggregation. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| toxin activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 4852.255 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P84038 |
| UniProtKB/Swiss-Prot Entry Name
| SLA_MACLB |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Sarray S, Srairi N, Hatmi M, Luis J, Louzir H, Regaya I, Slema H, Marvaldi J, El Ayeb M, Marrakchi N: Lebecetin, a potent antiplatelet C-type lectin from Macrovipera lebetina venom. Biochim Biophys Acta. 2003 Sep 23;1651(1-2):30-40. doi: 10.1016/s1570-9639(03)00232-2. [PubMed:14499586 ]
|
