| Identification |
|---|
| HMDB Protein ID
| HMDBP13390 |
| Secondary Accession Numbers
| None |
| Name
| Chymotrypsin-like elastase family member 1 |
| Synonyms
|
- Elastase-1
|
| Gene Name
| CELA1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Acts upon elastin. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| proteolysis |
| Cellular Component |
| extracellular space |
| Molecular Function |
| metal ion binding |
| serine-type endopeptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 266 |
| Molecular Weight
| 28821.345 |
| Theoretical pI
| 8.129 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P00772 |
| UniProtKB/Swiss-Prot Entry Name
| CELA1_PIG |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Talas U, Dunlop J, Khalaf S, Leigh IM, Kelsell DP: Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism. J Invest Dermatol. 2000 Jan;114(1):165-70. [PubMed:10620133 ]
- Shirasu Y, Yoshida H, Mikayama T, Matsuki S, Tanaka J, Ikenaga H: Isolation and expression in Escherichia coli of a cDNA clone encoding porcine pancreatic elastase. J Biochem. 1986 Jun;99(6):1707-12. doi: 10.1093/oxfordjournals.jbchem.a135646. [PubMed:3528137 ]
- Tani T, Kawashima I, Furukawa H, Ohmine T, Takiguchi Y: Characterization of a silent gene for human pancreatic elastase I: structure of the 5'-flanking region. J Biochem. 1987 Mar;101(3):591-9. doi: 10.1093/jb/101.3.591. [PubMed:3648024 ]
- Shotton DM, Hartley BS: Evidence for the amino acid sequence of porcine pancreatic elastase. Biochem J. 1973 Apr;131(4):643-75. doi: 10.1042/bj1310643. [PubMed:4578945 ]
- Shotton DM, Hartley BS: Amino-acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature. 1970 Feb 28;225(5235):802-6. doi: 10.1038/225802a0. [PubMed:5415108 ]
- Sawyer L, Shotton DM, Campbell JW, Wendell PL, Muirhead H, Watson HC: The atomic structure of crystalline porcine pancreatic elastase at 2.5 A resolution: comparisons with the structure of alpha-chymotrypsin. J Mol Biol. 1978 Jan 15;118(2):137-208. doi: 10.1016/0022-2836(78)90412-6. [PubMed:628010 ]
- Shotton DM, Watson HC: Three-dimensional structure of tosyl-elastase. Nature. 1970 Feb 28;225(5235):811-6. doi: 10.1038/225811a0. [PubMed:5415110 ]
- Huang K, Strynadka NC, Bernard VD, Peanasky RJ, James MN: The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase. Structure. 1994 Jul 15;2(7):679-89. doi: 10.1016/s0969-2126(00)00068-x. [PubMed:7922044 ]
|
