| Identification |
|---|
| HMDB Protein ID
| HMDBP13341 |
| Secondary Accession Numbers
| None |
| Name
| Pyrimidine/purine nucleoside phosphorylase |
| Synonyms
|
- Adenosine phosphorylase
- Cytidine phosphorylase
- Guanosine phosphorylase
- Inosine phosphorylase
- Thymidine phosphorylase
- Uridine phosphorylase
- Xanthosine phosphorylase
|
| Gene Name
| PPNP |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. |
| Pathways
|
- Biosynthesis of secondary metabolites
- Purine metabolism
- Pyrimidine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Molecular Function |
| purine-nucleoside phosphorylase activity |
| pyrimidine-nucleoside phosphorylase activity |
| thymidine phosphorylase activity |
| uridine phosphorylase activity |
| guanosine phosphorylase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 105 |
| Molecular Weight
| 11779.35 |
| Theoretical pI
| 4.879 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q186L5 |
| UniProtKB/Swiss-Prot Entry Name
| PPNP_CLOD6 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeno-Tarraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J: The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 2006 Jul;38(7):779-86. Epub 2006 Jun 25. [PubMed:16804543 ]
|
