| Identification |
|---|
| HMDB Protein ID
| HMDBP13340 |
| Secondary Accession Numbers
| None |
| Name
| Pyrimidine/purine nucleoside phosphorylase |
| Synonyms
|
- Adenosine phosphorylase
- Cytidine phosphorylase
- Guanosine phosphorylase
- Inosine phosphorylase
- Thymidine phosphorylase
- Uridine phosphorylase
- Xanthosine phosphorylase
|
| Gene Name
| PPNP |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. |
| Pathways
|
- Biosynthesis of secondary metabolites
- Purine metabolism
- Pyrimidine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Molecular Function |
| purine-nucleoside phosphorylase activity |
| pyrimidine-nucleoside phosphorylase activity |
| thymidine phosphorylase activity |
| uridine phosphorylase activity |
| guanosine phosphorylase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 94 |
| Molecular Weight
| 10234.335 |
| Theoretical pI
| 4.482 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A1A863 |
| UniProtKB/Swiss-Prot Entry Name
| PPNP_ECOK1 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Johnson TJ, Kariyawasam S, Wannemuehler Y, Mangiamele P, Johnson SJ, Doetkott C, Skyberg JA, Lynne AM, Johnson JR, Nolan LK: The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes. J Bacteriol. 2007 Apr;189(8):3228-36. doi: 10.1128/JB.01726-06. Epub 2007 Feb 9. [PubMed:17293413 ]
|
