| Identification |
|---|
| HMDB Protein ID
| HMDBP13215 |
| Secondary Accession Numbers
| None |
| Name
| Fructose-bisphosphate aldolase |
| Synonyms
|
- FBP aldolase
- FBPA
- 37 kDa major allergen
- Fructose-1,6-bisphosphate aldolase
- IgE-binding allergen
|
| Gene Name
| FBA1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Carbon metabolism
- Fructose and mannose metabolism
- glycolysis
- Glycolysis / Gluconeogenesis
- Methane metabolism
- Pentose phosphate pathway
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| gluconeogenesis |
| glycolysis |
| interaction with host |
| induction by symbiont of host defense response |
| Cellular Component |
| cytosol |
| plasma membrane |
| cell surface |
| fungal-type cell wall |
| hyphal cell wall |
| Molecular Function |
| zinc ion binding |
| fructose-bisphosphate aldolase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 359 |
| Molecular Weight
| 39215.1 |
| Theoretical pI
| 6.064 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9URB4 |
| UniProtKB/Swiss-Prot Entry Name
| ALF_CANAL |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Jones T, Federspiel NA, Chibana H, Dungan J, Kalman S, Magee BB, Newport G, Thorstenson YR, Agabian N, Magee PT, Davis RW, Scherer S: The diploid genome sequence of Candida albicans. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7329-34. doi: 10.1073/pnas.0401648101. Epub 2004 May 3. [PubMed:15123810 ]
- van het Hoog M, Rast TJ, Martchenko M, Grindle S, Dignard D, Hogues H, Cuomo C, Berriman M, Scherer S, Magee BB, Whiteway M, Chibana H, Nantel A, Magee PT: Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biol. 2007;8(4):R52. doi: 10.1186/gb-2007-8-4-r52. [PubMed:17419877 ]
- Muzzey D, Schwartz K, Weissman JS, Sherlock G: Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. 2013;14(9):R97. doi: 10.1186/gb-2013-14-9-r97. [PubMed:24025428 ]
|
