Hmdb loader
Identification
HMDB Protein ID HMDBP13186
Secondary Accession Numbers None
Name 1-deoxy-D-xylulose-5-phosphate synthase
Synonyms
  1. 1-deoxyxylulose-5-phosphate synthase
  2. DXP synthase
  3. DXPS
Gene Name DXS
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Pathways
  • 1-deoxy-D-xylulose 5-phosphate biosynthesis
  • Biosynthesis of secondary metabolites
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
Reactions Not Available
GO Classification
Biological Process
terpenoid biosynthetic process
thiamine biosynthetic process
1-deoxy-D-xylulose 5-phosphate biosynthetic process
Molecular Function
magnesium ion binding
thiamine pyrophosphate binding
1-deoxy-D-xylulose-5-phosphate synthase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 630
Molecular Weight 67123.215
Theoretical pI 5.345
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q4JVB5
UniProtKB/Swiss-Prot Entry Name DXS_CORJK
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Tauch A, Kaiser O, Hain T, Goesmann A, Weisshaar B, Albersmeier A, Bekel T, Bischoff N, Brune I, Chakraborty T, Kalinowski J, Meyer F, Rupp O, Schneiker S, Viehoever P, Puhler A: Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora. J Bacteriol. 2005 Jul;187(13):4671-82. doi: 10.1128/JB.187.13.4671-4682.2005. [PubMed:15968079 ]