| Identification |
|---|
| HMDB Protein ID
| HMDBP13126 |
| Secondary Accession Numbers
| None |
| Name
| Damage-control phosphatase ARMT1 |
| Synonyms
|
- Acidic residue methyltransferase 1
- Protein-glutamate O-methyltransferase
- Sugar phosphate phosphatase ARMT1
- Venom protein 2
|
| Gene Name
| VPR2 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity). Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity). Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (By similarity). Possibly methylates PCNA, suggesting it is involved in the DNA damage response (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| metal ion binding |
| fructose 6-phosphate aldolase activity |
| fructose-1-phosphatase activity |
| protein-glutamate O-methyltransferase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 55336.385 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q8MMH3 |
| UniProtKB/Swiss-Prot Entry Name
| ARMT1_PIMHY |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Parkinson NM, Conyers CM, Keen JN, MacNicoll AD, Smith I, Weaver RJ: cDNAs encoding large venom proteins from the parasitoid wasp Pimpla hypochondriaca identified by random sequence analysis. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Apr;134(4):513-20. doi: 10.1016/s1532-0456(03)00041-3. [PubMed:12727301 ]
|
