| Identification |
|---|
| HMDB Protein ID
| HMDBP13124 |
| Secondary Accession Numbers
| None |
| Name
| Fructose-bisphosphate aldolase 1 |
| Synonyms
|
- FBP aldolase 1
- FBPA 1
- Fructose-1,6-bisphosphate aldolase 1
|
| Gene Name
| FBA1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Carbon metabolism
- Fructose and mannose metabolism
- glycolysis
- Glycolysis / Gluconeogenesis
- Methane metabolism
- Pentose phosphate pathway
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| glycolysis |
| Molecular Function |
| zinc ion binding |
| fructose-bisphosphate aldolase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 360 |
| Molecular Weight
| 39631.655 |
| Theoretical pI
| 6.542 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q96UH7 |
| UniProtKB/Swiss-Prot Entry Name
| ALF1_PARBA |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Desjardins CA, Champion MD, Holder JW, Muszewska A, Goldberg J, Bailao AM, Brigido MM, Ferreira ME, Garcia AM, Grynberg M, Gujja S, Heiman DI, Henn MR, Kodira CD, Leon-Narvaez H, Longo LV, Ma LJ, Malavazi I, Matsuo AL, Morais FV, Pereira M, Rodriguez-Brito S, Sakthikumar S, Salem-Izacc SM, Sykes SM, Teixeira MM, Vallejo MC, Walter ME, Yandava C, Young S, Zeng Q, Zucker J, Felipe MS, Goldman GH, Haas BJ, McEwen JG, Nino-Vega G, Puccia R, San-Blas G, Soares CM, Birren BW, Cuomo CA: Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis. PLoS Genet. 2011 Oct;7(10):e1002345. doi: 10.1371/journal.pgen.1002345. Epub 2011 Oct 27. [PubMed:22046142 ]
- da Fonseca CA, Jesuino RS, Felipe MS, Cunha DA, Brito WA, Soares CM: Two-dimensional electrophoresis and characterization of antigens from Paracoccidioides brasiliensis. Microbes Infect. 2001 Jun;3(7):535-42. doi: 10.1016/s1286-4579(01)01409-5. [PubMed:11418327 ]
- Carneiro LC, de Faria FP, Felipe MS, Pereira M, de Almeida Soares CM: Paracoccidioides brasiliensis presents two different cDNAs encoding homologues of the fructose 1,6-biphosphate aldolase: protein isolation, cloning of the cDNAs and genes, structural, phylogenetic, and expression analysis. Fungal Genet Biol. 2005 Jan;42(1):51-60. doi: 10.1016/j.fgb.2004.10.003. [PubMed:15588996 ]
|
