| Identification |
|---|
| HMDB Protein ID
| HMDBP13108 |
| Secondary Accession Numbers
| None |
| Name
| 1-deoxy-D-xylulose-5-phosphate synthase |
| Synonyms
|
- 1-deoxyxylulose-5-phosphate synthase
- DXP synthase
- DXPS
|
| Gene Name
| DXS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). |
| Pathways
|
- 1-deoxy-D-xylulose 5-phosphate biosynthesis
- Biosynthesis of secondary metabolites
- Terpenoid backbone biosynthesis
- Thiamine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| terpenoid biosynthetic process |
| thiamine biosynthetic process |
| 1-deoxy-D-xylulose 5-phosphate biosynthetic process |
| Molecular Function |
| magnesium ion binding |
| thiamine pyrophosphate binding |
| 1-deoxy-D-xylulose-5-phosphate synthase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 632 |
| Molecular Weight
| 70234.205 |
| Theoretical pI
| 7.023 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A6L175 |
| UniProtKB/Swiss-Prot Entry Name
| DXS_BACV8 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Xu J, Mahowald MA, Ley RE, Lozupone CA, Hamady M, Martens EC, Henrissat B, Coutinho PM, Minx P, Latreille P, Cordum H, Van Brunt A, Kim K, Fulton RS, Fulton LA, Clifton SW, Wilson RK, Knight RD, Gordon JI: Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol. 2007 Jul;5(7):e156. doi: 10.1371/journal.pbio.0050156. Epub 2007 Jun 19. [PubMed:17579514 ]
|
