| Identification |
|---|
| HMDB Protein ID
| HMDBP13073 |
| Secondary Accession Numbers
| None |
| Name
| Phosphoglycerate kinase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| PGK1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. |
| Pathways
|
- Biosynthesis of amino acids
- Carbon metabolism
- glycolysis
- Glycolysis / Gluconeogenesis
- HIF-1 signaling pathway
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| gluconeogenesis |
| glycolysis |
| Cellular Component |
| cytosol |
| Molecular Function |
| ATP binding |
| ADP binding |
| phosphoglycerate kinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 417 |
| Molecular Weight
| 44614.36 |
| Theoretical pI
| 8.102 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| A5A6K4 |
| UniProtKB/Swiss-Prot Entry Name
| PGK1_PANTR |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Sakate R, Suto Y, Imanishi T, Tanoue T, Hida M, Hayasaka I, Kusuda J, Gojobori T, Hashimoto K, Hirai M: Mapping of chimpanzee full-length cDNAs onto the human genome unveils large potential divergence of the transcriptome. Gene. 2007 Sep 1;399(1):1-10. doi: 10.1016/j.gene.2007.04.013. Epub 2007 Apr 20. [PubMed:17574350 ]
|
