| Identification |
|---|
| HMDB Protein ID
| HMDBP13070 |
| Secondary Accession Numbers
| None |
| Name
| ATP-dependent 6-phosphofructokinase |
| Synonyms
|
- ATP-PFK
- Phosphofructokinase
- Phosphohexokinase
|
| Gene Name
| PFKA |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Carbon metabolism
- Fructose and mannose metabolism
- Galactose metabolism
- glycolysis
- Glycolysis / Gluconeogenesis
- Methane metabolism
- Microbial metabolism in diverse environments
- Pentose phosphate pathway
- RNA degradation
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| fructose 6-phosphate metabolic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| metal ion binding |
| ATP binding |
| 6-phosphofructokinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 337 |
| Molecular Weight
| 35688.92 |
| Theoretical pI
| 5.273 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| C0MGJ9 |
| UniProtKB/Swiss-Prot Entry Name
| PFKA_STRS7 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Holden MT, Heather Z, Paillot R, Steward KF, Webb K, Ainslie F, Jourdan T, Bason NC, Holroyd NE, Mungall K, Quail MA, Sanders M, Simmonds M, Willey D, Brooks K, Aanensen DM, Spratt BG, Jolley KA, Maiden MC, Kehoe M, Chanter N, Bentley SD, Robinson C, Maskell DJ, Parkhill J, Waller AS: Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens. PLoS Pathog. 2009 Mar;5(3):e1000346. doi: 10.1371/journal.ppat.1000346. Epub 2009 Mar 27. [PubMed:19325880 ]
|
