| Identification |
|---|
| HMDB Protein ID
| HMDBP13049 |
| Secondary Accession Numbers
| None |
| Name
| Pyridoxal 5'-phosphate synthase subunit PdxS |
| Synonyms
|
- PLP synthase subunit PdxS
- Pdx1
|
| Gene Name
| PDXS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. |
| Pathways
|
- Biosynthesis of cofactors
- pyridoxal 5'-phosphate biosynthesis
- Vitamin B6 metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| pyridoxal phosphate biosynthetic process |
| Molecular Function |
| pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 295 |
| Molecular Weight
| 31623.9 |
| Theoretical pI
| 4.765 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q2NI73 |
| UniProtKB/Swiss-Prot Entry Name
| PDXS_METST |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Fricke WF, Seedorf H, Henne A, Kruer M, Liesegang H, Hedderich R, Gottschalk G, Thauer RK: The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis. J Bacteriol. 2006 Jan;188(2):642-58. doi: 10.1128/JB.188.2.642-658.2006. [PubMed:16385054 ]
|
