| Identification |
|---|
| HMDB Protein ID
| HMDBP13014 |
| Secondary Accession Numbers
| None |
| Name
| Pyridoxal 5'-phosphate synthase subunit PdxS |
| Synonyms
|
- PLP synthase subunit PdxS
- Pdx1
|
| Gene Name
| PDXS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. |
| Pathways
|
- Biosynthesis of cofactors
- pyridoxal 5'-phosphate biosynthesis
- Vitamin B6 metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| pyridoxal phosphate biosynthetic process |
| Molecular Function |
| pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 287 |
| Molecular Weight
| 30288.46 |
| Theoretical pI
| 6.039 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q83MZ9 |
| UniProtKB/Swiss-Prot Entry Name
| PDXS_TROWT |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Raoult D, Ogata H, Audic S, Robert C, Suhre K, Drancourt M, Claverie JM: Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 2003 Aug;13(8):1800-9. doi: 10.1101/gr.1474603. [PubMed:12902375 ]
|
