| Identification |
|---|
| HMDB Protein ID
| HMDBP13008 |
| Secondary Accession Numbers
| None |
| Name
| Galactose-binding lectin-2 |
| Synonyms
|
- AKL-2
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, N-acetyllactosamine, D-galacturonic acid, D-galactose, methyl-alpha-D-galactoside, D-galactose, methyl-alpha-D-galactopyranoside, methyl-beta-D-galactopyranoside and lactose. Binds also the glycoproteins globotriose, asialofetuin and mucin. Possesses glycan-dependent cytotoxic activity against Burkitt's lymphoma Raji cells and erythroleukemia K562 cells. Has calcium-independent hemagglutinating activity towards human erythrocytes. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Molecular Function |
| carbohydrate binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 2700.05 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| B3EWI0 |
| UniProtKB/Swiss-Prot Entry Name
| LECG2_APLKU |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Kawsar SM, Matsumoto R, Fujii Y, Matsuoka H, Masuda N, Chihiro I, Yasumitsu H, Kanaly RA, Sugawara S, Hosono M, Nitta K, Ishizaki N, Dogasaki C, Hamako J, Matsui T, Ozeki Y: Cytotoxicity and glycan-binding profile of a D-galactose-binding lectin from the eggs of a Japanese sea hare (Aplysia kurodai). Protein J. 2011 Oct;30(7):509-19. doi: 10.1007/s10930-011-9356-7. [PubMed:21953532 ]
|
