| Identification |
|---|
| HMDB Protein ID
| HMDBP12959 |
| Secondary Accession Numbers
| None |
| Name
| 3-dehydroquinate dehydratase |
| Synonyms
|
- 3-dehydroquinase
- Type I DHQase
- Type I dehydroquinase
- DHQ1
|
| Gene Name
| AROD |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. |
| Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- chorismate biosynthesis
- Phenylalanine, tyrosine and tryptophan biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| cellular amino acid biosynthetic process |
| aromatic amino acid family biosynthetic process |
| chorismate biosynthetic process |
| Molecular Function |
| 3-dehydroquinate dehydratase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 235 |
| Molecular Weight
| 26697.14 |
| Theoretical pI
| 4.718 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q2NGS8 |
| UniProtKB/Swiss-Prot Entry Name
| AROD_METST |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Fricke WF, Seedorf H, Henne A, Kruer M, Liesegang H, Hedderich R, Gottschalk G, Thauer RK: The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis. J Bacteriol. 2006 Jan;188(2):642-58. doi: 10.1128/JB.188.2.642-658.2006. [PubMed:16385054 ]
|
