| Identification |
|---|
| HMDB Protein ID
| HMDBP12833 |
| Secondary Accession Numbers
| None |
| Name
| 4-hydroxythreonine-4-phosphate dehydrogenase |
| Synonyms
|
- 4-(phosphohydroxy)-L-threonine dehydrogenase
|
| Gene Name
| PDXA |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). |
| Pathways
|
- pyridoxine 5'-phosphate biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| pyridoxine biosynthetic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| NAD binding |
| metal ion binding |
| 4-hydroxythreonine-4-phosphate dehydrogenase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 364 |
| Molecular Weight
| 40324.575 |
| Theoretical pI
| 5.338 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q89ZK3 |
| UniProtKB/Swiss-Prot Entry Name
| PDXA_BACTN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Xu J, Bjursell MK, Himrod J, Deng S, Carmichael LK, Chiang HC, Hooper LV, Gordon JI: A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science. 2003 Mar 28;299(5615):2074-6. doi: 10.1126/science.1080029. [PubMed:12663928 ]
|
