Hmdb loader
Identification
HMDB Protein ID HMDBP12696
Secondary Accession Numbers None
Name Probable diguanylate cyclase DgcQ
Synonyms
  1. DGC
  2. Cellulose synthesis regulatory protein
Gene Name DGCQ
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity).
Pathways
  • 3',5'-cyclic di-GMP biosynthesis
  • bacterial cellulose biosynthesis
Reactions Not Available
GO Classification
Biological Process
cellulose biosynthetic process
Cellular Component
integral to membrane
plasma membrane
Molecular Function
metal ion binding
GTP binding
diguanylate cyclase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 570
Molecular Weight 65479.125
Theoretical pI 9.192
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • 20-40;360-380;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q5PLI4
UniProtKB/Swiss-Prot Entry Name DGCQ_SALPA
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]