| Identification |
|---|
| HMDB Protein ID
| HMDBP12691 |
| Secondary Accession Numbers
| None |
| Name
| Factor V activator RVV-V alpha |
| Synonyms
|
- Russel's viper venom FV activator alpha
- Snake venom serine protease
- RVV-V alpha
- SVSP
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Venom serine protease that activates factor V (F5) in a calcium-independent manner. It cleaves the Arg(1545)-Ser(1546) linkage in the human factor V molecule. Induces the coagulation of mammalian plasma. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| extracellular region |
| Molecular Function |
| toxin activity |
| serine-type endopeptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 26181.885 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P18964 |
| UniProtKB/Swiss-Prot Entry Name
| VSPA_DABSI |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Segers K, Rosing J, Nicolaes GA: Structural models of the snake venom factor V activators from Daboia russelli and Daboia lebetina. Proteins. 2006 Sep 1;64(4):968-84. doi: 10.1002/prot.21051. [PubMed:16807918 ]
- Tokunaga F, Nagasawa K, Tamura S, Miyata T, Iwanaga S, Kisiel W: The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-V alpha, -V beta, and -V gamma and their complete amino acid sequences. J Biol Chem. 1988 Nov 25;263(33):17471-81. [PubMed:3053712 ]
|
