| Identification |
|---|
| HMDB Protein ID
| HMDBP12671 |
| Secondary Accession Numbers
| None |
| Name
| 3-dehydro-bile acid delta(4,6)-reductase |
| Synonyms
|
Not Available
|
| Gene Name
| BAIN |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Involved in the secondary bile acid metabolism. Catalyzes two subsequent reductions of the double bonds within the bile acid A/B rings of 3-oxochol-4,6-dien-24-oyl-CoA and 12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA to yield 3-oxocholan-24-oyl-CoA and 12alpha-hydroxy-3-oxocholan-24-oyl-CoA, respectively. |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| bile acid catabolic process |
| lipid catabolic process |
| Molecular Function |
| oxidoreductase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 409 |
| Molecular Weight
| 44416.58 |
| Theoretical pI
| 8.381 |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| B0NAQ4 |
| UniProtKB/Swiss-Prot Entry Name
| BAIN_CLOS5 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Harris SC, Devendran S, Alves JMP, Mythen SM, Hylemon PB, Ridlon JM: Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Mar;1863(3):276-283. doi: 10.1016/j.bbalip.2017.12.001. Epub 2017 Dec 5. [PubMed:29217478 ]
|
