| Identification |
|---|
| HMDB Protein ID
| HMDBP12654 |
| Secondary Accession Numbers
| None |
| Name
| Endothelin-converting enzyme 1 |
| Synonyms
|
- ECE-1
|
| Gene Name
| ECE1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Converts big endothelin-1 to endothelin-1. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| proteolysis |
| peptide hormone processing |
| protein processing |
| Cellular Component |
| integral to membrane |
| plasma membrane |
| membrane |
| Molecular Function |
| metal ion binding |
| protein homodimerization activity |
| endopeptidase activity |
| metalloendopeptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 85516.095 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P42891 |
| UniProtKB/Swiss-Prot Entry Name
| ECE1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Schmidt M, Kroger B, Jacob E, Seulberger H, Subkowski T, Otter R, Meyer T, Schmalzing G, Hillen H: Molecular characterization of human and bovine endothelin converting enzyme (ECE-1). FEBS Lett. 1994 Dec 19;356(2-3):238-43. doi: 10.1016/0014-5793(94)01277-6. [PubMed:7805846 ]
- Boratko A, Vereb Z, Petrovski G, Csortos C: TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation. Int J Biochem Cell Biol. 2016 Apr;73:11-18. doi: 10.1016/j.biocel.2016.01.016. Epub 2016 Jan 22. [PubMed:26806547 ]
|
