| Identification |
|---|
| HMDB Protein ID
| HMDBP12597 |
| Secondary Accession Numbers
| None |
| Name
| Renin |
| Synonyms
|
- Angiotensinogenase
|
| Gene Name
| REN |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Cellular Component |
| membrane |
| extracellular region |
| Molecular Function |
| aspartic-type endopeptidase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 45057.125 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P60016 |
| UniProtKB/Swiss-Prot Entry Name
| RENI_PANTR |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Dufour C, Casane D, Denton D, Wickings J, Corvol P, Jeunemaitre X: Human-chimpanzee DNA sequence variation in the four major genes of the renin angiotensin system. Genomics. 2000 Oct 1;69(1):14-26. doi: 10.1006/geno.2000.6313. [PubMed:11013071 ]
|
