| Identification |
|---|
| HMDB Protein ID
| HMDBP12529 |
| Secondary Accession Numbers
| None |
| Name
| Arginine deiminase |
| Synonyms
|
- ADI
- Arginine dihydrolase
- Streptococcal acid glycoprotein
- AD
|
| Gene Name
| ARCA |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Antitumor protein. Has a powerful and dose-dependent inhibitory effect on antigen, superantigen, or mitogen-stimulated human peripheral blood mononuclear cell (PBMC) proliferation. It may inhibit cell proliferation by arresting cell cycle and inducing apoptosis (By similarity). |
| Pathways
|
- L-arginine degradation via ADI pathway
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| arginine catabolic process to ornithine |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| arginine deiminase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 46296.41 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P0C0B3 |
| UniProtKB/Swiss-Prot Entry Name
| ARCA_STRPY |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Kanaoka M, Negoro T, Kawanaka C, Agui H, Nabeshima S: Streptococcal antitumor protein: expression in Escherichia coli cells and properties of the recombinant protein. Agric Biol Chem. 1991 Mar;55(3):743-50. [PubMed:1368629 ]
|
