Hmdb loader
Identification
HMDB Protein ID HMDBP12349
Secondary Accession Numbers None
Name Acetyltransferase CD1211
Synonyms
  1. GCN5-related N-acetyltransferase
  2. GNAT
Gene Name (GENBANK) PUTATIVE N-ACETYLTRANSFERASE
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers L-threonine, L-serine and L-methionine. It can also use O-acetyl-L-serine, L-tryptophan, L-isoleucine, L-valine, L-homoserine, 7-aminocephalosporanic acid, thiamine pyrophosphate and thiamine.
Pathways Not Available
Reactions Not Available
GO Classification
Molecular Function
transferase activity, transferring acyl groups other than amino-acyl groups
N-acetyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 159
Molecular Weight 18435.26
Theoretical pI 6.194
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q18B70
UniProtKB/Swiss-Prot Entry Name ATSE_CLOD6
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeno-Tarraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J: The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 2006 Jul;38(7):779-86. Epub 2006 Jun 25. [PubMed:16804543 ]
  2. Kuhn ML, Majorek KA, Minor W, Anderson WF: Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity. Protein Sci. 2013 Feb;22(2):222-30. doi: 10.1002/pro.2199. Epub 2012 Dec 17. [PubMed:23184347 ]